Chemical Composition, In Vitro Antioxidant Activities, and Inhibitory Effects of the Acetylcholinesterase of Liparis nervosa (Thunb.) Lindl. Essential Oil

The present study aimed to investigate the essential oil composition of Liparis nervosa (Thunb.) Lindl., grown in China, and determine its antioxidant inhibitory effects on acetylcholinesterase. was obtained by hydrodistillation, chemical compounds were analyzed GC-MS GC-FID. We used 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS), 2,2-diphenyl-1-picrylhydrazyl (DPPH), ferric reducing assay power (FRAP) evaluate activity. anti-acetylcholinesterase activity also examined. Sixty-seven identified, representing 98.50 % total oil, which shown be rich methyl (9E,11E)-octadeca-9,11-dienoate (31.69%), n-hexadecanoic acid (15.08%), isopropyl palmitate (12.44%), propyl tetradecanoate (7.20%), tetradecanoic (4.01%), 17-octadecynoic (3.71%), pentacosane (2.24%). Its ability via ABTS (IC50 = 721.95 ± 9.93 μg/mL), DPPH scavenging capacity > 10,000 FRAP method (Trolox equivalent concentration 39.64 3.38 μM/g). Acetylcholinesterase inhibition evaluated had an IC50 value 51.96 14.26 μg/mL. results show that this has interesting biological potential, encouraging further investigations, especially regarding mechanisms action This is first time composition, activity, acetylcholinesterase from L. have been studied.